5-Fluorocytosine (5-FC), antifungal agent (CAS 2022-85-7) (ab141197) (2024)

Overview

• Product name

  5-Fluorocytosine (5-FC), antifungal agent

• Description

  Antimycotic prodrug

• Alternative names

  • 5-FC

• Biological description

  Antimycotic prodrug, converted to 5-fluorouracil. Disrupts DNA and RNA synthesis. Displays antifungal and antitumor activity. Active in vivo.

• Purity

  > 99%

• CAS Number

  2022-85-7

• Chemical structure

  

Properties

• Chemical name

  4-Amino-5-fluoropyrimidine-2(1H)-one

• Molecular weight

  129.09

• Molecular formula

  C₄H₄FN₃O

• PubChem identifier

  3366

• Storage instructions

  Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.

• Solubility overview

  Soluble in DMSO to 50 mM and in water to 50 mM

• Handling

  Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  Toxic, refer to SDS for further information

  Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

• SMILES

  FC1=CNC(=O)N=C1N

• Source

  Synthetic

• Research areas

  • Cell Biology
  • Apoptosis
  • Intracellular
  • Bcl2 Family

  • Immunology
  • Innate Immunity
  • Cytokines
  • Interferons

  • Cell Biology
  • Apoptosis
  • Intracellular
  • Caspases etc
  • Caspases

  • Signal Transduction
  • Signaling Pathway
  • Nuclear Signaling
  • Nuclear Hormone Receptors
  • Testosterone

  • Epigenetics and Nuclear Signaling
  • Nuclear Signaling Pathways
  • Nuclear Receptors
  • Testosterone

  • Stem Cells
  • Signaling Pathways
  • TGF beta
  • Interferon gamma

  • Cancer
  • Invasion/microenvironment
  • Apoptosis
  • Bcl 2 family

  • Cancer
  • Invasion/microenvironment
  • Apoptosis
  • Caspases

  • Cancer
  • Signal transduction
  • Nuclear signaling
  • Nuclear hormone receptors
  • Other

  • Cancer
  • Tumor immunology
  • Cytokines
  • Interferons

  • Immunology
  • Adaptive Immunity
  • Regulatory T Cells

  • Developmental Biology
  • Reproduction
  • Hormones

  • Microbiology
  • Antimicrobial
  • Antibiotic

  • Cancer
  • Cancer Metabolism
  • Response to hypoxia

  • Biochemicals
  • Product Range
  • Just Add Water

  • Biochemicals
  • Chemical Type
  • Biochemicals

  • Biochemicals
  • Chemical Type
  • Antibiotic

  • Metabolism
  • Pathways and Processes
  • Metabolism processes
  • Hypoxia

  • Metabolism
  • Pathways and Processes
  • Metabolism processes
  • Apoptosis

  • Biochemicals
  • Pharmacology
  • Signaling

  • Biochemicals
  • Research Area
  • Cancer

  • Biochemicals
  • Pharmacology
  • Signaling
  • Immunomodulators
  • Antifungal

  • Cancer
  • Cell Death
  • Apoptosis
  • Apoptosis Markers
  • Bcl 2 family

  • Cancer
  • Cell Death
  • Apoptosis
  • Apoptosis Markers
  • Caspases

  • Cancer
  • Cell Death
  • Apoptosis
  • Metabolism

• Chemical Structure - 5-Fluorocytosine (5-FC), antifungal agent (ab141197)

  2D chemical structure image of ab141197, 5-Fluorocytosine (5-FC), antifungal agent

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

• SDS download

  Country/Region

  Language

  

• Datasheet download

  Download

• COA

ab141197 has not yet been referenced specifically in any publications.